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Nonprescription weight-loss supplements. There are many more diet pills available that aren't FDA-approved or -regulated. "Federal law does not require dietary supplements to be proven safe to FDA's satisfaction before they are marketed," the FDA's website says. Dec 12, 2016 · When selecting a weight loss supplement, you should always go for purely natural options that stem from plants, herbs and fruits. In comparison to the artificial alternatives, herbal slimming pills don’t cause such serious complications. Additionally, these organic weight loss pills choices contain vitamins and minerals that help you lose weight.